If its just race fuel, then no you will not have to change anything. Although, I don't know about all those crazy oxygenated mixtures and stuff that those drag guys use though.
yes brad i sure do.i run it 100% of the time actually.the ama only allows a certain amount of oxy content though i believe 2.55% so check it out first if you are gonna race nats or keep your can hidden!i also use unleaded not the leaded fuel it is better for the injectors .